> For the complete documentation index, see [llms.txt](https://pennprs.gitbook.io/pennprs/llms.txt). Markdown versions of documentation pages are available by appending `.md` to page URLs; this page is available as [Markdown](https://pennprs.gitbook.io/pennprs/user-manual.md).

# User Manual

<figure><img src="https://2442862337-files.gitbook.io/~/files/v0/b/gitbook-x-prod.appspot.com/o/spaces%2FUJXTPxJsaKahj9yvWoaZ%2Fuploads%2F9hkaQ0ic7qUkvTGZ1TcI%2FScreenshot%202025-02-07%20at%209.13.33%E2%80%AFPM.png?alt=media&amp;token=cfbd93d2-d869-4a15-8d70-ca8ae907115f" alt=""><figcaption></figcaption></figure>

The PennPRS computing platform supports online training of PRS models based on various methods. Currently, our AWS-based online server supports six single-ancestry PRS methods and one multi-ancestry PRS method.&#x20;

We recognize the rapid methodological development in the field and are committed to continuing to update our platform to implement state-of-the-art algorithms. If you have recommendations for additional methods/algorithms to be included in our platform, please feel free to contact us at <pennprs@googlegroups.com>. We appreciate your feedback and support as we work diligently to implement more methods and improve your experience on our website.