Introduction

Welcome to PennPRS.

PennPRS offers a cloud-based ecosystem for PRS applications, including pseudo-training pipelines, data resources, and cloud computing capabilities to support large-scale PRS model training.

PennPRS enables efficient online applications of pseudo-training methods, allowing users to upload or query GWAS summary statistics, submit jobs, and download trained PRS models. It provides a user-friendly framework for the global genetic research community, aiming to enhance the accessibility of PRS applications and address disparities in computational resources. Specifically, we develop end-to-end pipelines to support both single-ancestry and multi-ancestry data analyses. More details of these pipelines are provided in the User Manual.

The PennPRS Team